| |
Originales
|
| EFFECT OF GASTRIC BYPASS ON THE METABOLIC SYNDROME AND ON CARDIOVASCULAR RISK |
| J. Ocón, B. García, P. Benito, S. Gimeno, R. García Y P. López |
| Nutr Hop. 2010;25(1):67-71 doi:10.3305/nh.2010.25.1.4179 |
 PDF (80,8kb)
|
| Abstract |
| Background: Obesity is associated with increased morbimortality cardiovascular. Individual with metabolic syndrome (MS) are a high risk of developing cardiovascular disease (CVD). The aim of this study was to determine the prevalence of the MS in morbidly obese patients enrolling in a bariatric surgery program and to evaluate the impact of weigh loss induced by gastric bypass on the MS and on the predicted 10-year cardiovascular risk.
Material and methods: We studied 46 morbidly obese patients who underwent laparoscopic gastric bypass and were followed for 2 years. MS was defined following the IDF 2005 criteria and the insulin resistance (IR) was calculated by using HOMA index. Risk assessment for estimating 10-year ECV risk was carried out according to Framingham score.
Results: Before surgery, 67, 2% of patients had IR and 60,9% met the definition of the MS. 17.3% of patients had an elevated cardiovascular risk category. 2 years after gastric bypass, the percentage of excess body weight lost was 72%. All patients restored their HOMA index and only 1 patient (3,6%) had MS. Resolution of hypertension, disglucemia and dislipemia has been observed in 85%, 93,8% and 95,6% of patients. Estimated cardiovascular risk decreased from 4,5% at baseline to 1% at 2 years after surgery.
Conclusions: SM is common in morbidly obese patients. Bypass gastric is associated with an improvement or resolution in cardiovascular risk factors and IR and result in a significant reduction in MS prevalence and of predicted 10-year cardiovascular risk.
|
|
| |
 ||  |
|
