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Originales
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| Relation between leptin serum with weight and body fat distribution in post menopausal women. |
| Y. Barrios, N. Díaz, L. Meertens, G. Naddaf, L. Solano, M.ª Fernández, A. Flores Y M.ª González |
| Nutr Hop. 2010;25(1):80-84 doi:10.3305/nh.2010.25.1.4273 |
 PDF (81,3kb)
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| Abstract |
| Leptin is a peptidic hormone secreted by the fat tissue
and plays an important role in body weight regulation.
After menopause, weight gain increases as well as android-
like obesity. Previous studies suggest a relationship
between leptin level, body mass index (BMI) and fat
distribution.
Objective: To establish the relationships between
serum leptin, BMI, waist circumference (WC), and
waist/hip ratio (WHR).
Methodology: 48 women under the age of 60 years and
with amenorrhea for longer than one year were assessed.
Leptin and estradiol (ELISA) levels were determined;
normal values: 3.63-11.09 ng/mL and 0-65 pg/Ml. BMI
(WHO), WC > 88 cm, and WHR > 0.80 were considered
as indicators of cardiometabolic risk.
Results: Mean age for the group was 54 ± 3.9 years;
leptin: 8.4 ± 3.7 ng/mL, and estradiol: 17.6 ± 10.0 pg/mL;
BMI: 27.0 ± 4.9 kg/m2; WC: 86.2 ± 8.6 cm; and WHR:
0.84 ± 0.06. Twenty percent of the women had hyperleptinemia,
58.4% malnourishment due to excessive intake,
35% presented WC cardiovascular risk. The highest
leptin value was found in obese women. There was no
association between serum leptin levels and anthropometrical
variables. There was a significantly positive
correlation between weight, height, BMI, WC, hip circumference,
and estradiol.
Conclusions: Postmenopausal women presented a
high prevalence of overweight/obesity, android-like body
fat distribution and normal serum leptin levels. The
group assessed is considered to be at risk for cardiometabolic
diseases according to anthropometrical indicators. |
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