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Originales
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| RANDOMIZED CLINICAL TRIAL WITH A INULIN ENRICHED COOKIE ON RISK CARDIOVASCULAR FACTOR IN OBESE PATIENTS |
| D. A. De Luis, B. De La Fuente, O. Izaola, R. Conde, S. Gutiérrez, M.ª Morillo Y C. Teba Torres |
| Nutr Hop. 2010;25(1):53-59 doi:10.3305/nh.2010.25.1.4535 |
 PDF (85,4kb)
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| Abstract |
| Introduction: Inulin is a prebiotic with potential benefit in cardiovascular risk factors. The aim of our work is to evaluate in obese patients the effect of a inulin enriched cookie on cardiovascular risk factors.
Material and methods: 34 patients were randomized in both branches: group I (inulin enriched cookie) Gullon SL ® and group II (control cookie). Previous and after 1 month of the treatment, a nutritional and biochemical study was realized.
Results: 15 patients finished the procotol in each group. In group I, an increase in soluble fiber intake (inulin) was detected. In this group a significant decrease of total cholesterol (223,1+/-45,3 mg/dl vs 208,8+/-33,1 mg/dl;p<0,05) and LDL cholesterol (142,9+/-39,2 mg/dl vs 131,4+/-28,6 mg/dl;p<0,05) was reached. A non significant improvement in insulin levels and HOMA was detected in inulin-enriched cookie group, too. Anthropometric parameters did not change in both groups. The increase in soluble fiber intake did not produce any gastrointestinal adverse effect.
Conclusion: The increase of fiber intake (3 g of inulin) from an enriched cookie reduced LDL cholesterol levels in obese patients.
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